Plasma Fibroblast Growth Factor 23 Is Elevated in Pediatric Primary Hypertension
نویسندگان
چکیده
منابع مشابه
Elevated fibroblast growth factor 23 is a risk factor for kidney transplant loss and mortality.
An increased circulating level of fibroblast growth factor 23 (FGF23) is an independent risk factor for mortality, cardiovascular disease, and progression of chronic kidney disease (CKD), but its role in transplant allograft and patient survival is unknown. We tested the hypothesis that increased FGF23 is an independent risk factor for all-cause mortality and allograft loss in a prospective coh...
متن کاملFibroblast Growth Factor 23 Is Associated With Subclinical Cerebrovascular Damage
Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that regulates phosphate homeostasis and when elevated increases cardiovascular disease and stroke risk and mortality. However, most studies of FGF23 have focused on those with chronic kidney disease (CKD). Less data are available from the general population, especially with respect to stroke. We previously reported elevated FGF23 in...
متن کاملHow fibroblast growth factor 23 works.
There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that are caused by either high or low circulating levels of the novel phosphaturic hormone fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of FGF23 are characterized by hypophosphatemia, decreased production of 1,25-dihydroxyvitamin D, and rickets/osteomalacia. On th...
متن کاملA Case of Hyperphosphatemia and Elevated Fibroblast Growth Factor 23: A Brief Review of Hyperphosphatemia and Fibroblast Growth Factor 23 Pathway
Joseph Wang, Beth Vogt, Sidharth Kumar Sethi, Matthew G. Sampson, Virginia Vega-Warner, Edgar A. Otto and Rupesh Raina Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania, USA; Pediatric Nephrology, Rainbow Babies and Children’s Hospital at Case Western Reserve University, Cleveland, Ohio, USA; Pediatric Nephrology, Kidney Institute, Medanta, The Medicity, Gurgaon, Haryana, India, 122...
متن کاملFibroblast growth factor-23 (FGF-23) is independently correlated to aortic calcification in haemodialysis patients.
BACKGROUND Vascular calcification has detrimental consequences on chronic kidney disease (CKD) patients, yet its pathogenesis is not fully understood. Fibroblast growth factor-23 (FGF-23) is involved in the regulation of mineral metabolism which may in turn affect vascular calcification. Data on the relationship between FGF-23 and peripheral vascular calcification, using conventional radiograph...
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ژورنال
عنوان ژورنال: Frontiers in Pediatrics
سال: 2019
ISSN: 2296-2360
DOI: 10.3389/fped.2019.00135